IV Ketamine Therapy

A fast-acting treatment option for depression, PTSD, and anxiety.

What Is IV Ketamine Therapy?

Ketamine is a well-known anesthetic that, when used at low doses in a clinical setting, has shown rapid antidepressant and anti-anxiety effects. IV ketamine therapy involves delivering a precise, sub-anesthetic dose of ketamine through an intravenous (IV) infusion. Unlike traditional medications that take weeks to work, ketamine may relieve symptoms within hours or days.

Ketamine therapy is typically reserved for people with treatment-resistant mental health conditions — those who haven’t found relief with standard care. It is not a daily medication, but rather a supervised, time-limited treatment protocol designed to support brain-based recovery.

Conditions IV Ketamine Therapy May Help With

Ketamine therapy may be considered for individuals diagnosed with:
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Treatment-Resistant Depression (TRD)

Depression that has not improved after trying multiple antidepressants

Post-Traumatic Stress Disorder (PTSD)

Persistent symptoms following trauma that haven’t responded to standard care

Generalized Anxiety Disorder (GAD)

Ongoing, excessive worry that has not improved with traditional therapy or medications

While not FDA-approved for psychiatric conditions, IV ketamine is used off-label under medical supervision with growing research support.

Who Might Benefit From Ketamine Therapy

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IV ketamine may be an option for people who:
  • Have tried multiple medications or therapies without relief
  • Experience side effects that limit their ability to continue conventional treatment
  • Struggle with persistent symptoms that interfere with everyday life
  • Are looking for a treatment with a different mechanism of action than traditional antidepressants
Your eligibility will be carefully evaluated by a medical provider before starting ketamine therapy.

How the Treatment Works

Ketamine is administered via IV in a controlled, clinical setting. It is delivered slowly over a set period while the patient rests in a comfortable, monitored room.

Here’s what a typical treatment protocol includes:

Initial Series

6–8 infusions over 2–4 weeks

Session Length

40–60 minutes per infusion, plus recovery time

Monitoring

Vital signs and mental state are tracked throughout

Follow-Up Care

Booster infusions may be offered based on your response

During treatment, some patients experience mild dissociation or shifts in perception — these effects are temporary and closely monitored.

Safety and Side Effects

IV ketamine therapy is medically supervised to ensure safety and minimize risks. Common side effects are generally short-lived and may include:

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  • Mild nausea
  • Dizziness or lightheadedness
  • Dissociative sensations during the infusion
  • Temporary increase in blood pressure or heart rate
  • Fatigue or emotional sensitivity post-session
Patients are carefully screened before beginning treatment, and you will need a ride home after each infusion.

What to Expect From Results

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Ketamine therapy often works differently — and faster — than traditional antidepressants. Many people begin to feel a shift in mood, clarity, or anxiety levels within the first few treatments.

Key points to know:

  • Response varies — not everyone feels better right away, but many report meaningful improvement
  • Effects are cumulative and may require ongoing sessions for maintenance
  • Follow-up care and therapeutic support are important for long-term results
  • Relief from symptoms may be felt in days, not weeks
For many people who have tried everything else, ketamine therapy represents a hopeful new chapter.

Why Lumora

At Lumora, we help patients access advanced psychiatric treatments through a network of trusted clinics. We are not a provider — we’re a partner in making care accessible, safe, and understandable.

When you pursue IV ketamine therapy through Lumora:

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  • You’re connected to licensed clinics with medical supervision and psychiatric expertise
  • You receive education and support throughout your treatment journey
  • We help remove the friction and confusion from finding next-level care
  • Every decision is guided by clarity, safety, and compassion
You don’t have to navigate the next step alone — we’re here to help make it make sense.

Explore whether IV ketamine therapy is right for you.

Contact Us

We’re here to help you take the next step toward feeling better.

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